Analysis of repeated measurements and time-to-event data via random
effects joint models. Fits the joint models proposed by Henderson and colleagues
<doi:10.1093/biostatistics/1.4.465> (single event time) and by Williamson and
colleagues (2008) <doi:10.1002/sim.3451> (competing risks events time) to a
single continuous repeated measure. The time-to-event data is modelled using a
(cause-specific) Cox proportional hazards regression model with time-varying
covariates. The longitudinal outcome is modelled using a linear mixed effects
model. The association is captured by a latent Gaussian process. The model is
estimated using am Expectation Maximization algorithm. Some plotting functions
and the variogram are also included. This project is funded by the Medical
Research Council (Grant numbers G0400615 and MR/M013227/1).
Version: |
1.2.8 |
Depends: |
R (≥ 3.6), survival |
Imports: |
graphics, lattice, MASS, nlme, statmod, stats, utils |
Suggests: |
knitr, rmarkdown, testthat, covr |
Published: |
2023-01-22 |
DOI: |
10.32614/CRAN.package.joineR |
Author: |
Pete Philipson
[aut] (<https://orcid.org/0000-0001-7846-0208>),
Ines Sousa [aut]
(<https://orcid.org/0000-0002-2712-1713>),
Peter J. Diggle
[aut] (<https://orcid.org/0000-0003-3521-5020>),
Paula Williamson
[aut] (<https://orcid.org/0000-0001-9802-6636>),
Ruwanthi Kolamunnage-Dona
[aut]
(<https://orcid.org/0000-0003-3886-6208>),
Robin Henderson [aut],
Graeme L. Hickey
[aut, cre] (<https://orcid.org/0000-0002-4989-0054>),
Maria Sudell [ctb],
Medical Research Council [fnd] (Grant numbers: G0400615 and
MR/M013227/1) |
Maintainer: |
Graeme L. Hickey <graemeleehickey at gmail.com> |
BugReports: |
https://github.com/graemeleehickey/joineR/issues |
License: |
GPL-3 | file LICENSE |
URL: |
https://github.com/graemeleehickey/joineR/ |
NeedsCompilation: |
no |
Citation: |
joineR citation info |
Materials: |
README NEWS |
In views: |
Survival |
CRAN checks: |
joineR results |