Fit and compare nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'rxode2' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
Version: |
3.0.1 |
Depends: |
nlmixr2data |
Imports: |
nlmixr2est (≥ 2.2.2), nlmixr2extra (≥ 2.0.10), rxode2 (≥
2.1.3), lotri (≥ 0.4.3), nlmixr2plot (≥ 2.0.8), magrittr, crayon, cli |
Suggests: |
rmarkdown, knitr, devtools, ggplot2, testthat, n1qn1, withr |
Published: |
2024-10-28 |
DOI: |
10.32614/CRAN.package.nlmixr2 |
Author: |
Matthew Fidler
[aut, cre] (<https://orcid.org/0000-0001-8538-6691>),
Yuan Xiong [ctb],
Rik Schoemaker
[ctb] (<https://orcid.org/0000-0002-7538-3005>),
Justin Wilkins
[ctb] (<https://orcid.org/0000-0002-7099-9396>),
Wenping Wang [ctb],
Mirjam Trame [ctb],
Huijuan Xu [ctb],
John Harrold [ctb],
Bill Denney [ctb]
(<https://orcid.org/0000-0002-5759-428X>),
Theodoros Papathanasiou [ctb],
Teun Post [ctb],
Richard Hooijmaijers [ctb] |
Maintainer: |
Matthew Fidler <matthew.fidler at gmail.com> |
BugReports: |
https://github.com/nlmixr2/nlmixr2/issues/ |
License: |
GPL (≥ 3) |
URL: |
https://nlmixr2.org/, https://github.com/nlmixr2/nlmixr2/ |
NeedsCompilation: |
no |
Citation: |
nlmixr2 citation info |
Materials: |
README NEWS |
In views: |
DifferentialEquations, HighPerformanceComputing, MixedModels, Pharmacokinetics |
CRAN checks: |
nlmixr2 results |