grantham: Calculate the Grantham Distance
A minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
| Version: | 0.1.2 |
| Depends: | R (≥ 2.10) |
| Imports: | tibble, vctrs, dplyr |
| Suggests: | spelling, testthat (≥ 3.0.0) |
| Published: | 2024-07-30 |
| DOI: | 10.32614/CRAN.package.grantham |
| Author: | Ramiro Magno 
[aut, cre] (<https://orcid.org/0000-0001-5226-3441>),
Isabel Duarte
[aut] (<https://orcid.org/0000-0003-0060-2936>),
Ana-Teresa Maia
[aut] (<https://orcid.org/0000-0002-0454-9207>),
University of Algarve [fnd],
CINTESIS [fnd],
Pattern Institute [cph, fnd] |
| Maintainer: | Ramiro Magno <rmagno at pattern.institute> |
| BugReports: | https://github.com/patterninstitute/grantham/issues |
| License: | MIT + file LICENSE |
| URL: | https://www.pattern.institute/grantham/, https://github.com/patterninstitute/grantham |
| NeedsCompilation: | no |
| Language: | en-US |
| Materials: | README NEWS |
| CRAN checks: | grantham results |
Documentation:
| Reference manual: | grantham.pdf |
Downloads:
| Package source: | grantham_0.1.2.tar.gz |
| Windows binaries: | r-devel: grantham_0.1.2.zip, r-release: grantham_0.1.2.zip, r-oldrel: grantham_0.1.2.zip |
| macOS binaries: | r-release (arm64): grantham_0.1.2.tgz, r-oldrel (arm64): grantham_0.1.2.tgz, r-release (x86_64): grantham_0.1.2.tgz, r-oldrel (x86_64): grantham_0.1.2.tgz |
| Old sources: | grantham archive |
Reverse dependencies:
| Reverse imports: | agvgd |
Linking:
Please use the canonical form https://CRAN.R-project.org/package=grantham to link to this page.